QUESTION: A pregnant woman developed German Measles infection in her 1st trimester. Which of the following congenital abnormalities may appear in the foetus?
a. Renal agenesis
b. cleft palate
c. Limb deformities
d. Cleft lip
e. congenital cataract
Answer: e
Explanation:
German measles = Rubella
Rubella is one of the more teratogenic viruses. Congenital rubella syndrome (CRS) is characterized by intrauterine growth restriction, intracranial calcifications, microcephaly, cataracts, cardiac defects (most commonly patent ductus arteriosus or pulmonary arterial hypoplasia), neurologic disease (with a broad range of presentations, from behavior disorders to meningoencephalitis), osteitis, and hepatosplenomegaly.
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